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Clinical application of paediatric serum troponin T testing
  1. Claire McGinn1,2,
  2. Chris Watson1,
  3. Gareth McKeeman3,
  4. Bethany Mauger1,
  5. Louise Morrison2,
  6. Frank A Casey1,2
  1. 1Queen's University Belfast Wellcome-Wolfson Institute for Experimental Medicine, Belfast, UK
  2. 2Paediatric Cardiology, Royal Belfast Hospital for Sick Children, Belfast, UK
  3. 3Clinical Biochemistry, Belfast Health and Social Care Trust, Belfast, UK
  1. Correspondence to Dr Claire McGinn, Queen's University Belfast Wellcome-Wolfson Institute for Experimental Medicine, Belfast, UK; cmcginn09{at}

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Cardiac ischaemia is rare in children, and acute presentations of chest pain are multifactorial. Serum troponin testing may be used to aid diagnosis of suspected cardiac ischaemia in both children and adults; however, the literature suggests there is limited value in serum troponin testing in paediatric patients presenting with chest pain.1 2

We conducted a single-centre review of all troponin T (TnT) laboratory requests from paediatric patients up to their 16th birthday from 19 September 2017 to 21 September 2022. 354 samples were included in the final analysis. Table 1 describes the yield of elevated serum troponin results based on common presenting complaints and the subsequent incidence of a cardiac diagnosis. A serum TnT>10 ng/L was considered elevated based on the …

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  • X @gcmckeeman

  • Contributors CMG co-designed the study, performed data collection and wrote the article. GMcK and BM performed data collection and reviewed the article. CW, FAC and LM co-designed the study and reviewed then article.

  • Funding This study was funded by Royal Belfast Hospital for Sick Children Charitable funds.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.