Article Text

Download PDFPDF
Should we use weight-based vitamin D treatment in children?
  1. Fawaz Arshad1,2,
  2. Paul Arundel3,
  3. Nicholas Bishop2,3,
  4. Stephanie Borg2,3
  1. 1Sheffield Children's NHS Foundation Trust, Sheffield, UK
  2. 2Department of Oncology and Metabolism, The University of Sheffield, Sheffield, UK
  3. 3Metabolic Bone Team, Sheffield Children's NHS Foundation Trust, Sheffield, UK
  1. Correspondence to Dr Fawaz Arshad, Sheffield Children's NHS Foundation Trust, Sheffield, UK; fawaz.arshad{at}nhs.net

Statistics from Altmetric.com

Vitamin D deficiency (VDD) is a perennial problem in the UK.

The Royal Osteoporosis Society (ROS) guideline for treatment of VDD, defined as 25-hydroxyvitamin D (25-OHD) <25 nmol/L, is1:

  • 1–5 months: 3000 international units (IU)/day for 8–12 weeks;

  • 6 months to 11 years: 6000 IU/day for 8–12 weeks

  • ≥12 years: 10 000 IU/d for 8–12 weeks

  • alternative ≥12 years: 300 000 IU/day total in single or divided dose

This is supported by the British Society of Paediatric Endocrinology and Diabetes and the RCPCH vitamin D resource page.

We planned to determine whether treatment resulted in an increase in serum 25-OHD to over 50 nmol/L and how this related to dose/kg.

A retrospective review of consecutive patient records referred to our paediatric bone …

View Full Text

Footnotes

  • Contributors PA devised the project. FA collected the data. FA analysed the data with input from PA, NB and SB. FA wrote the manuscript with input from all authors.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.