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Update on the management of a newborn with a suspected difference of sex development
  1. Angela K Lucas-Herald1,
  2. Martina E Rodie2,3,
  3. S Faisal Ahmed1
  1. 1Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
  2. 2Office for Rare Conditions, University of Glasgow, Glasgow, UK
  3. 3Department of Neonatology, Queen Elizabeth University Hospital Campus, Glasgow, UK
  1. Correspondence to Professor S Faisal Ahmed, Developmental Endocrinology Research Group, University of Glasgow, Glasgow G51 4TF, UK; faisal.ahmed{at}glasgow.ac.uk

Abstract

Differences or disorders of sex development are a group of heterogeneous conditions, which most commonly present in the newborn period, with the appearance of atypical genitalia on newborn examination. Over recent years, the improvement in our knowledge of these conditions has been accompanied by advances in diagnostic technology and therapeutic options, as well as societal shifts in attitudes and expectations. These factors have placed an even greater emphasis than before on the need for early expert input through a multidisciplinary service that can support the patient and the family; perform and interpret the investigations required to reach a diagnosis; and formulate a management plan that lays down the foundation for optimal long-term outcome. While providing a regional service, the expert team should also be committed to research and quality improvement through participation in national and international networks.

  • neonatology
  • endocrinology
  • genetics

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No data are available. No original data used.

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Data availability statement

No data are available. No original data used.

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Footnotes

  • Contributors All authors contributed equally to the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors. Angela Lucas-Herald is funded by a joint NES/CSO Clinical Lectureship. Martina Rodie is funded by the Glasgow Children's Hospital Charity.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; externally peer reviewed.

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