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COVID-19: lessons learned from a paediatric high consequence infectious diseases unit
  1. Elizabeth Whittaker1,2,
  2. Ruchi Sinha1
  1. 1 Imperial College Healthcare NHS Trust, London, UK
  2. 2 Section of Paediatric Infectious Diseases, Imperial College London, London, UK
  1. Correspondence to Dr Elizabeth Whittaker, Imperial College Healthcare NHS Trust, London W2 1NY, UK; elizabeth.whittaker2{at}nhs.net

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In 2018, the government commissioned four paediatric and five adult airborne high consequence infectious diseases (HCID) units in preparation for the emergence of a new airborne viral infection in the UK. St Mary’s Hospital (Imperial College Healthcare NHS Trust), London was one of the paediatric centres, partnered with the Royal Free Hospital for adults. St Mary’s was ideally placed to look after children with possible airborne HCID, with a newly designed and built suite of HCID rooms and an expert and collaborative group of paediatric intensivists and infectious diseases consultants. It was exciting to prepare for these eventualities, which felt unlikely as we focused instead on Brexit and the environment. In retrospect, I am ashamed of thinking that this would be exciting, as we now live through a pandemic whose proportions go well beyond my wildest nightmare.

In mid-January 2020, all trusts in England were contacted by the chief medical officer with advice about ‘Wuhan Novel Coronavirus’, later named SARS-CoV-2. The four key principles were to identify possible cases as soon as possible, isolate to prevent transmission to other patients and staff, avoid direct physical contact unless wearing appropriate personal protective equipment, and get specialist advice from a local microbiologist, virologist or infectious disease physician at your local trust. At this time, there were 10 confirmed cases outside of China and none in Europe. Locally, preparations were underway both at a trust level and locally within paediatrics. Together with the site team, adequate supplies of personal protective equipment (PPE) were identified and training exercises prepared for immediate response teams in donning and doffing protocols. A programme for ‘fit-testing’ all staff members for FFP3 respiratory masks was initiated. Algorithms for management of suspected cases presenting to all areas of the trust, including adult and paediatric A+E, ambulatory care and maternity services, were prepared. Together with our adult HCID partner, the Royal Free Hospital, we rapidly amended standard operating protocols for admission of confirmed cases.

Shortly afterwards, as an HCID, we were contacted by NHS England (NHSE) specialised commissioning to ringfence a bed for a confirmed case, and ensure all resources were available to provide clinical and nursing support for that bed. Regular paediatric HCID teleconferences hosted by NHSE were established weekly to ensure standardised approaches and identify areas of need/challenges.

The following day, the first case in the UK was diagnosed. Over the next few days, we ran simulation exercises with the children’s acute transport services and the National ambulance resilience unit, as well as locally with our team (infection control, site managers, security, estates, cleaning, nursing and medical team members). A first version of trust guidance for management of paediatric suspected and confirmed cases was drafted. The nursing and clinical rotas were addressed to ensure the right mix of staff would be available for every shift. Pandemic ‘table-top’ exercises and workforce planning were time-tabled.

Reassuringly, all data from China suggested that children were the age group least affected by coronavirus disease 2019 (COVID-19). However, it quickly became apparent from frequent advice calls and emails from regional colleagues in district general hospitals, community care and primary care that we had quite a head start in preparations due to our position as an HCID. As the situation developed and a pandemic was declared, it became worryingly clear that there were many challenges to ensure safe care for children, despite their relatively safe status, both regionally and nationally. Here, I collate some of the challenges faced to date, some of the current solutions, and importantly, what we can do to be ready for any future pandemics, particularly those which may affect children as significantly as COVID-19 affects older patients (table 1). I expand in detail on two areas specific to paediatrics and which due to our role as an HCID centre we have the ability to address as a contingency for future outbreaks; the use of PPE and ongoing workforce planning/training.

Table 1

Summary of challenges faced by paediatric services during COVID-19 outbreak

One of the main areas of anxiety for healthcare workers has been access to, and adequacy of, PPE. Guidance about the use of PPE is published by national public health bodies (eg, Public Health England (PHE)). As the SARS-CoV-2 virus was originally designated as a HCID, the highest level of PPE was recommended for all possible interactions. As further information about the virus, such as the method of transmission (droplet spread) became available, the PPE guidance was appropriately changed, both internationally by WHO and nationally. However, this led to confusion and misinformation, as many felt that the decision to downgrade the choice of PPE was due to stock shortages, confounded by difficulties distributing PPE by procurement teams nationally as so many healthcare settings ordered it simultaneously.

The PPE recommended for high-risk contact with SARS-CoV-2 included FFP3 mask, visor, long-sleeved fluid-resistant gown and gloves. There are clear guidelines about how to safely don and doff PPE of this type, including ensuring that the FFP3 mask fits appropriately.1 Although at ICHT, ‘fit-testing’ of FFP3 masks for critical care and inpatient ward staff and training in how to safely don and doff PPE started in January, there were still concerns that we had inadequate numbers of our workforce trained to care for patients by the time a pandemic was announced, and many centres had not yet started to prepare their workforce. A number of staff were unable to ‘pass’ fit-testing, both due to issues with the testing method and as not all face sizes and shapes suited the mask available locally. Furthermore, as procurement became more challenging, a variety of shapes and brands of FFP3 mask were delivered, all of which ideally required further rounds of ‘fit-testing’, a very time-consuming task. But as staff safety is paramount, and as this has been on the agenda at every internal meeting attended (four times a day), the daily ICHT staff update email, every local, regional, national and international webinar on COVID-19 and the majority of news headlines and social media discussions over the last 2 months, finding a better strategy is crucial.

On discussion with medical colleagues in Canada who had first-hand experience of the first SARS outbreak in 2003/2004, it transpired that all Canadian healthcare staff are ‘fit-tested’ with a variety of mask types as part of induction training for each job and had regular mandatory fit-testing reviews to ensure their safety in the event of needing to wear this type of PPE.2 As such, recommending that all healthcare settings stock a selection of mask shapes and types, and that all staff undergo mandatory fit-testing regularly seems proportionate. Alongside this, regular training and refresher sessions of donning and doffing PPE, including for simulated resuscitation scenarios is recommended. It is proposed that scenarios involving patients presenting unwell with a possible airborne HCID are routine in simulation educational programmes nationally.

Up-to-date training and skills required for containing epidemic-type diseases must be better integrated into the training of all healthcare professionals, not only those specialising in infectious diseases, or working in an HCID centre. Establishing formal networks using a hub-and-spoke approach from the HCID centres to identify, transfer and rapidly ‘upskill’ experienced healthcare professionals in the event of future outbreaks could result in more rapid ‘upskilling’ of staff in the event of another major pandemic. The team in an HCID centre, composed of key clinicians, nurses, pharmacists, allied healthcare professionals and possibly even security and cleaners, should practise regular simulations. These sessions could include training for healthcare workers from other centres and in addition, web-based training materials should be developed for online training.

It is clearly unreasonable, both from a financial and practicality perspective, to have the capacity to admit 20 000 extra patients generated as part of a ‘once-in-a-lifetime’ pandemic at all times in England. This would divert essential funding from other areas of the national health service. However, it is reasonable to be ready to rapidly upskill and change routine practice flexibly and with ease to accommodate this potential cohort, and having a prepared workforce is key to this.

Further to this, we recommend that paediatric training includes critical care training for all, and all paediatric intensive care trainees should do secondments to adult intensive care (and vice versa).

Although I highlight challenges, the most striking thing about this outbreak has been the willingness of all staff to work towards a single aim, minimising the impact on children. Supporting our colleagues to continue to do this, and indeed to do it as safely as possible, is vital.

Acknowledgments

We are grateful to Andrew Riordan, Stephen Owens and Alicia Demirijan for their helpful comments on the manuscript

References

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Footnotes

  • Contributors EW and RS discussed the content of the paper, EW prepared a first draft and RS edited and added points from a critical care perspective.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Commissioned; internally peer reviewed.

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