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Should gonadotropin releasing hormone analogue be administered to prevent premature ovarian failure in young women with systemic lupus erythematosus on cyclophosphamide therapy?
  1. Rajiv Sinha (rajivsinha_in{at}
  1. British Columbia's Children's Hospital, Canada
    1. Janis M Dionne
    1. British Columbia's Children's Hospital, Canada


      1) Young women suffering from SLE treated with CYC have a high risk of ovarian failure. [Grade C]

      2) GnRH is a promising option for ovarian preservation in SLE but should currently be regarded as an experimental therapy.

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