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Letter
Thyroid screening in Down’s syndrome: current patterns in the UK
  1. S Varadkar,
  2. G Bineham,
  3. D Lessing
  1. Hounslow & Spelthorne Community & Mental Health NHS Trust and West Middlesex University Hospital, Isleworth, UK
  1. Correspondence to:
    Dr S Varadkar, Biochemistry, Endocrinology and Metabolism Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK;
    sophia{at}varadkar.co.uk

https://doi.org/10.1136/adc.88.7.647

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    Children and adults with Down’s syndrome are at increased risk of developing thyroid dysfunction, and screening for thyroid dysfunction is recommended as part of their health surveillance.1 Clinical history and examination are known to be unreliable indicators of thyroid dysfunction in Down’s syndrome. Venous blood for thyroid stimulating hormone (TSH) assay remains the gold standard. Capillary blood spot on filter paper TSH has been proposed as a simpler and more convenient alternative screening method …

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