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Hypertrophic pyloric stenosis of infancy is a disorder of early infancy with typical clinical features and well-established radiological appearance of the pyloric canal. Many studies with surgical and medical treatment have been reported over the past fifty years. Pylorotomy has tended to become the favoured method of treatment as with expert paediatric, surgical, anaesthetic, and nursing services and specialised accommodation for infants, the outcome is good with low mortality, short stay in hospital and few complications. However, a variety of studies of medical treatment with anticholinergic drugs and successful outcomes in some large series of cases have also been reported from Sweden, United States of America and the United Kingdom.
Since 1996 this group of workers from Osaka, Japan, has revived an interest in medical treatment with reports of a new regime using methyl atropine nitrate intravenously. To achieve satisfactory short …