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Letter
Procalcitonin as a prognostic marker in children with meningococcal septic shock
  1. F Leclerc,
  2. S Leteurtre,
  3. O Noizet,
  4. A Dorkenoo,
  5. A Sadik,
  6. R Cremer,
  7. C Fourier
  1. Paediatric Intensive Care Unit, University Hospital of Lille, Lille, France
  1. Correspondence to:
    Professor Leclerc, Hôpital Jeanne de Flandre, 59037, Lille, France;
    fleclerc{at}chru-lille.fr

https://doi.org/10.1136/adc.87.5.450

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    Carrol and coworkers1 confirm the findings from Karabocuoglu et al who reported that procalcitonin (PCT) was higher in children with severe meningococcaemia (fever, petechia or purpura, and hemodynamic instability) than in children with systemic meningococcal infection without shock (291.29 ± 167 v 19.7 ± 23 ng/ml; p<0.001).2

    Unfortunately, information is lacking in the report of Carrol et al,1 namely: a clear definition of severe MCD (defined in their paper as a Glasgow Meningococcal Septicaemia Prognostic Score ≥8) and median PCT values of survivors and non-survivors and comparison in term of prediction of outcome between PCT level and generic or specific severity scoring systems. We report that admission PCT level is an accurate predictor of mortality in the subgroup of children with …

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