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Intestinal inflammation in cystic fibrosis
  1. N M CROFT
  1. R L SMYTH,
  2. U O'HEA
  1. T G MARSHALL
  1. Department of Paediatric Gastroenterology
  2. St Bartholomew's and the Royal London School of Medicine and Dentistry
  3. Queen Mary and Westfield College, London, UK
  4. Institute of Child Health
  5. Royal Liverpool Children's Hospital
  6. Liverpool L12 2AP, UK
  7. Royal Hospital for Sick Children
  8. Edinburgh, UK

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Editor,—We thank Dr Briars for his recent comments and are aware of his opinions regarding the potential source of the intestinal cytokines that we discussed in paper, including reference to his previous paper.1

We do not agree that our data is dependant upon IL-8 alone. We have shown statistically significant differences for a whole range of proteins and types of assays. Due to the large number of proteins and types of assays that we have performed, we have not carried out the extensive experiments for IL-8, as reported by Dr Briars. We do know that the polyethylene glycol, a key constituent …

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