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Preliminary clinical evaluation of meningococcal disease and bacterial meningitis by ultrasonic enhancement
  1. R A Barnesa,
  2. P Jenkinsb,
  3. W T Coakleyb
  1. aDepartment of Medical Microbiology and PHLS, University of Wales College of Medicine, Cardiff, bSchool of Pure and Applied Biology, University of Wales, Cardiff
  1. Dr Rosemary A Barnes, Department of Medical Microbiology, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN. e-mail:Barnesra{at}cardiff.ac.uk

Abstract

Antigen detection in the urine and serum may be useful in the diagnosis of suspected meningococcal disease, especially after previous antibiotic treatment. Current test card procedures using commercial agglutination kits are often too insensitive to contribute to diagnosis. Diagnosis of meningococcal disease rose from 37% with the test card procedure to 74% following ultrasonic enhancement.

  • meningococcal disease
  • diagnosis
  • ultrasound enhancement
  • antigen detection

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