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O-082 Epidemic Gradient Of Severe Bronchiolitis From Paris Region To East And West Of France. Retrospective Study
  1. AL Virlouvet1,
  2. S Essouri2,
  3. AS Guilbert2,
  4. A Garenne3,
  5. E Sauleau4,
  6. M Schaeffer4,
  7. P Desprez1
  1. 1Réanimation Pédiatrique, Hopital de Strasbourg, Strasbourg, France
  2. 2Réanimation Pédiatrique, Hopital Du Kremlin-Bicêtre, Kremlin-Bicêtre, France
  3. 3Réanimation Pédiatrique, Hopital de Brest, Brest, France
  4. 4Département d’information Médicale, Hopital de Strasbourg, Strasbourg, France


In France, 2000 to 4000 infants are admitted each year in intensive care units for bronchiolitis, leading to a temporary increase of the activity. Anticipating this epidemic would greatly improve health care organisation in those units. Following a clinical observation, this study aimed to highlight a delay in the epidemic in the East of France compared to the West and a similarity in the severity of each epidemic. Retrospectively were included all the infants with a clinical and severe bronchiolitis hospitalised in intensive care units in the Brest, Kremlin-Bicêtre (KB) and Strasbourg university hospitals, one year in two from 2006 to 2013, between July, 1st and and June, 30th. 434 infants were included: 43 in Brest, 291 in KB and 100 in Strasbourg. Populations were comparable in terms of birth’s weight, term, history, sex-ratio, age, RSV rate, complication rate and death. Ventilation was longer in Strasbourg. The severity of epidemics was comparable during each period with a an admission ratio compared to KB of 15%* in Brest and 34%* in Strasbourg (*p < 0,05).

Abstract O-082 Figure 1

Admissions number in intensive care units in Bresh, Kremlin-Bicêtre and Strasbourg during each period

Epidemic occurred with a delay of 2 to 5 weeks in Strasbourg, and 2 to 7 weeks in Brest. The severe cases of bronchiolitis appear several weeks earlier in KB than in Strasbourg and Brest, with a comparable severity every year in these three regions. The observation of the situation in KB allows for anticipating the severity and date of the epidemic in Brest and Strasbourg.

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