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PO-0574 Indications And Outcomes Of Lumbar Punctures In Term Neonates In A Tertiary Neonatal Unit
  1. H Wood,
  2. E Seager,
  3. J Gray,
  4. SV Rasiah
  1. Neonatology, Birmingham Women’s NHS Foundation Trust, Birmingham, UK


Background Lumbar puncture (LP) is usually performed when there is a clinical suspicion of meningitis in babies with suspected sepsis. NICE recently published their guidelines on ‘antibiotics for early-onset neonatal infections’ with guidance on when LPs should be considered.

Aim To audit the indications and outcomes of LPs performed in term babies (>37 + 0 weeks) in a tertiary neonatal unit.

Methods A list of term babies who had an LP was obtained from the Microbiology Department between 01/01/2010 and 31/12/2013. The Badger electronic patient record and hospital blood results systems were reviewed to collect the data.

Results In the last 4 years we had 2,882 term babies admitted to the neonatal unit. 136 LPs were performed in 133 term babies. The reasons for LPs were; (a) raised CRP in 106 cases (median CRP was 70), (b) abnormal neurology in 18 cases, (c) positive blood culture in 8 cases and (d) 4 were for no other clinical focus. There was one culture of coliforms and another positive for herpes simplex virus type 1 on PCR. At discharge, 8 had a diagnosis of meningitis and 1 with encephalitis.

Conclusion The predominant indication for LPs in term babies was a raised CRP. We only isolated organisms from two samples. As per NICE guidance, we rely on a combination of clinical findings and CRPs when deciding which term babies to LP.

References Antibiotics for early-onset neonatal infectionNICE

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