Introduction Neonatal sepsis is a common and potentially serious neonatal disease especially in preterm babies and more complicated in developing countries.
Objectives To study the incidence and the microbial pattern of neonatal sepsis in our unit in Amman/Jordan.
Method A retrospective study of all newborn cases admitted to our NICU as suspected sepsis over a 4-year period, 2001–2004 analysing the results of blood cultures.
Results The total number of newborns delivered in our NICU over a 4-year period was 25715.
- 819 (3.2%) babies were admitted as suspected sepsis. *616(75%) were full term babies. *203 (25%) were preterm babies (28 to 36 weeks)
- The total culture- proven cases (positive blood cultures) were 51 (6.2%).out of which 21(40%) cases were preterm babies. So culture-proven sepsis was found in about 10% of preterm babies and in about 5% of full term babies who were admitted as suspected sepsis.
- The overall incidence of sepsis was 2 per 1000.
- Gram negative organisms recovered in 32 cases (63%),mainly Klebsiella species in 21 cases (40%), E.coli in 7(14%)and Pseudomonas in 4 cases (8%).
- Gram positive cases were 19(37%) : Staphylococci aureus in 7 cases, Staph. Epidermidis in 4, GBS in 5 and Strept.viridans in 3 cases.
The mortality among all culture-proven cases was 2 cases (4%).
Conclusion - A bout 3.2% of all newborns were admitted as suspected sepsis.
- Only 6% of suspected cases of sepsis were proven culture positive-The overall incidence of neonatal sepsis in our unit is 2/1000.
- Klebsiella species is the commonest pathogen isolated in our NICU.
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