Background and aims Hypoxic Ischaemic Encephalopathy (HIE) is associated with high levels of mortality and disability. A multicenter randomised control trial (TOBY Study), showed therapeutic hypothermia (TH) increased survival without adverse neurological outcome, with only minor adverse events. The study was conducted in Level 2 (local) and Level 3 (intensive care) Neonatal units (NNUs), the majority of TH is now carried out in Level 3 NNUs, which is reflected in national guidance. Exeter and Truro local NNUs cooled 45 infants over a 34-month period. Results are presented.
Methods Retrospective audit of 45 infants who underwent TH for HIE in two local NNUs (Exeter n = 28, Truro n = 17). Cooling practices were audited against TOBY Trial criteria and NICE guidance for the first time.
Conclusions We suggest TH can be carried out effectively and safely in Local NNUs with appropriate training and expertise.
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