Introduction This study was conducted to determine pain relief using non- pharmacalogical strategy during routine ROP screening conducted in a clinical setting.

Methodology An observational, exploratory quantitative study of 28 ROP screenings was performed in a NICU level III. Pain assessment tools were Premature Infant Pain Profile (PIPP) and Skin Conductance Algesimeter (SCA). Non- pharmacalogical strategy included a fed and content infant, swaddled and nested in a physiological position. Facilitated tucking provided of a nurse including use of pacifier and sucrose 24% regularly every third minute.

Results Both PIPP and SCA showed that group 1; the first eye of the first time ROP screening the infant expressed no pain to any fraction of the examination. Group 2; examination of the second eye of the first ROP screening together with all the following examinations both PIPP and SCA detect increased pain.

Conclusion Using non- pharmacalogical strategy during ROP screening appears to have some pain relief. However, no firm conclusion can be drawn due to the uncertain variables.