Background Thermal protection is critical in caring very low birthweight (VLBW).
Methods VLBW infants born at Chang-Gung Memorial Hospital were randomly assigned to TB or control group from February to July 2013. All infants were placed on a pre-warmed radiant warmer upon admission. For TB group, blanket of Blanketrol ® II (Cincinnati Sub-Zero Products) was additionally applied (Figure 1) and system temperature was set 37°C. Individual’s temperature, heart rate, mean blood pressure (MAP), and oxygen saturation were measured immediately at admission and at 30th, 60th, 90th, 120th minute later, respectively. We defined hypothermia as temperature <36°C and hypotension as MAP < index infant’s gestational age (GA).
Results Total 80 VLBW infants (mean GA 28.9 ± 3.0 weeks and birthweight 1062 ± 247 gm) were allocated at 1:1 ratio. There was no between-group demographic dissimilarity, and the percentage of hypothermia was identical at admission. At 30th minute, fewer infants in TB group had hypothermia (43% vs. 68% in control, p = 0.025) (Figure 2). These infants had significantly lower incidence of hypotension at 60th, 90th, and 120th minute, which associated with less dopamine use in the first 6 h of life (25% vs. 50%, p = 0.016).
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