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Obesity and appetite genes

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If obesity was all due to genetics, then we wouldn't be seeing the huge and rapid increase apparent today. However, although the obesogenic environment is a major factor, some estimates suggest that genetics could be responsible for as much as 50% of the problem. If that's true, what is the mechanism? There is increasing evidence that behavioural, rather than metabolic factors might be important, and that these may operate from a very early age. Two related studies published in JAMA Pediatrics add support to this view. Both are …

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  • Competing interests None.

  • Provenance and peer review Commissioned; internally peer reviewed.