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At the threshold
If you could get a multiplex PCR result back to you within 2 h that told you your hot, grumpy, 2-month-old patient did not have bacteraemia, would you discontinue antibiotics?
How sure would you need to be of that result—95% certain? 98% certain? 99.5% certain?
What—in diagnostic analysis speak—would be your ‘threshold’?
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