You are here

Article Text

Article menu
Download PDFPDF
Archimedes
Question 2: Is there any long-term benefit from injecting botulinum toxin-A into children with cerebral palsy?
  1. Lyndon J Bradley,
  2. James S Huntley
  1. Royal Hospital for Sick Children Glasgow, Glasgow, UK
  1. Correspondence to Lyndon J Bradley, Royal Hospital for Sick Children Glasgow, Glasgow G3 8SJ, UK; lyndonbradley@clear.net.nz

https://doi.org/10.1136/archdischild-2013-305805

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Clinical scenario

    A 5-year-old girl with diplegic cerebral palsy has been seen regularly since the age of 3 years. As part of the management for lower limb spasticity, she has undergone three previous intramuscular botulinum toxin A injections (BoTN-A) to her gastrocnemii. During the consent process for a further injection, the mother asks if this treatment will be of benefit to her daughter in the future.

    Clinical question

    In children with cerebral palsy receiving intramuscular injection of BoTN-A is there any clinically relevant long-term (greater than 1 year) effect?

    Search

    A literature search was performed in January 2013 using MEDLINE, PubMed and the Cochrane Database (table 1). The population identifier of ‘cerebral palsy’ and intervention of either botulinum toxin(s), Botulinum, BoNT-A, BoNT-B, BtA, BtB, BT, Botox or Dysport was used, limited to English language, from the year 1993 and the age limit of child (0–18 years) (N=2159). This was then restricted to ‘randomised controlled trials’ (N=58). These were …

    View Full Text

    Footnotes

    • Competing interests None.

    • Provenance and peer review Commissioned; internally peer reviewed.

    Linked Articles