Statistics from Altmetric.com
Complete androgen insensitivity syndrome (CAIS) is an X-linked recessive disorder resulting from an androgen receptor mutation. Affected individuals have 46,XY karyotype but female phenotype are raised as girls.1 A short vagina and absent uterus result in infertility, likely psychosexual problems and a risk of later gonadal malignancy such that gonadectomy is recommended.2 Presentation may be in adolescence with primary amenorrhoea, but 1% of premenstrual phenotypic girls with inguinal hernia (IH) will have CAIS.3 Despite current recommendations4 ,5 that all premenstrual girls with IH should be screened for CAIS, a survey6 of 32 UK paediatric surgeons found that 63% do not mention CAIS to their parents at any stage and 43% made no …
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.