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1510 A Study of the Value of Sleep Eeg Record in Predicting Seizure Recurrence in Children with a Single Afebrile Seizure
  1. J Chukwu1,2,
  2. P Gallagher3,
  3. B McCoy3,
  4. D Webb3
  1. 1Molecular & Cellular Therapeutics, Royal College of Surgeons
  2. 2Clinical Research Unit, National Children’s Research Centre
  3. 3Neurology, Our Lady’s Children’s Hospital, Dublin, Ireland


Aims The main aim of the study was to determine the value of a sleep EEG recording in predicting the risk of epilepsy in children with a single afebrile seizure.

Methods A retrospective review of 69 children who underwent sleep EEG recordings in 2007 following their first afebrile seizure was undertaken. Parents were sent a questionnaire on seizure recurrence, diagnosis of epilepsy, anti-epileptic medication use, further EEGs and school progress.

Results Fifty two (52) questionnaires (75%) were completed and returned. Twenty three of the fifty two children (44%) have had one or more further seizures - 7/25 (28%) of those with normal sleep EEG recordings and 14/21 (67%) of those who had abnormal sleep EEG recordings. 6/52 (12%) of the respondents had suspicious EEG and 2 of these have had further seizures. 12/21 (57%) of those with abnormal sleep EEGs compared with 5/25(20%) of those with normal EEG have had multiple further seizures.

Pearson-Chi Square revealed a significant relationship between abnormal EEG and the development of further seizures (p<0.01). The odds of having further seizures if the EEG was abnormal was 4.9 (95% C.I 1.5–16.1).

Conclusions Sleep EEG is a useful tool in predicting the risk of developing epilepsy in children with first afebrile seizure.

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