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1381 Gastrointestinal Perforations in Neonatal Period
  1. E Blevrakis1,
  2. C Seremeti1,
  3. N Partalis1,
  4. O Dede1,
  5. A Alegakis2,
  6. E Korakaki3,
  7. C Gianakopoulou3,
  8. G Sakellaris1
  1. 1Department of Paediatric Surgery, University Hospital of Heraklion, Crete
  2. 2Department of Toxicology, University of Crete
  3. 3Neonatal Intensive Care Unit, University Hospital of Heraklion, Crete, Heraklion, Greece


Aim This report describes our experience concerning gastrointestinal perforation (GI) due to Necrotizing enterocolitis (NEC) during a 10 year period.

Method The cases of 27 GI perforations, which were treated in our hospital, were retrospectively reviewed.

Results All patients were neonates and infants up to the age of 2 months. The study population consisted of 16 boys (59.3%) and 11 girls (40.7%). Twenty one (77.8%) neonates were pre-term and the median gestational age was 28 weeks. Twenty four (88.9%) cases of perforation underwent laparotomy. The overall mortality was 63%. Seventy six percent of the pre-term neonates and only 16.7% of the full-term died.

Conclusions GI perforation is still connected with a high mortality rate, with NEC being the main cause of death. The neonates who did not undergo surgery all died.

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