Article Text
Abstract
Objectives
To study the pattern of pathogens causing UTI in children in Jordan.
To study the frequency of E. coli resistance to antibiotics.
Settings and method A prospective study of all cases of UTI presented to our pediatric department both in-patient and out-patient over two years (2010 and 2011). Studying the age and sex, the causative pathogens and their sensitivity and resistance to antibiotics. RESULTS: Age: Under 1 year of age 26 cases (21%), 1–5 years :51 cases(42%). Above 5 years: 37 cases (32%).
Sex Females 94 cases (82%), Males 20 cases (18%). The ratio of 4.7:1.
The total number of cases was 114 including: 79 cases of E.Coli(64%), 29 cases of Klebsiella sp.(23%),7 cases of Enterobacter sp.(6%), 5 cases of Proteus sp.(4%), 2 cases of Staphylococcus aureus (2%) and 1 case of Pseudomonas sp.(1%).
The following antibiotics were administered according to the sensitivity of E. Coli and other factors:
Amikacin in 29 cases (36%), Cefixim 27 cases (34%), Amoxy-clav. 13 cases(17%).
Cephtriaxone 4 cases (5%),Cefpodoxime 3 cases(4%), Cefuroxime 3 cases. (4%).
Conclusion UTIs are more common in girls and in toddlers.
E. coli is the commonest organism causing UTI followed by Klebsiella sp.
*Parenteral Amikacin was the drug of choice in about one third of cases of UTIs caused by E. coli which were resistant to the previously used antibiotics.
*Cefixim is the best oral antibiotic followed by Amoxy-clav.