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Varicella postexposure prophylaxis in children with cancer: urgent need for a randomised controlled trial
  1. Jessica Bate1,
  2. Julia Chisholm2,
  3. Roderick Skinner3,
  4. Judy Breuer4,
  5. Mary Ramsay5,
  6. Keith Wheatley6,
  7. Sophie Hambleton7,
  8. Paul T Heath1
  1. 1Division of Clinical Sciences, St Georges University of London, London, UK
  2. 2Children and Young People’s Unit, Royal Marsden NHS Foundation Trust, Sutton, UK
  3. 3Department of Paediatric and Adolescent Oncology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK
  4. 4Department of Virology, University College, London, UK
  5. 5Department of Immunisation, Hepatitis and Blood Safety, Health Protection Agency, London, UK
  6. 6Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, UK
  7. 7Institute of Cellular Medicine, Newcastle University, Newcastle, UK
  1. Correspondence to Dr Jessica Bate, Department of Child Health, St Georges University of London, Cranmer Terrace, London SW17 0RE, UK; jbate{at}

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We welcome the interest of Samuelson et al1 in our work on prevention of varicella in children with cancer.2 However, they misrepresent our method for estimating the incidence of VZV exposure requiring PEP, which did not rely on consultant recollection. As described in detail in our paper, this was achieved by painstaking scrutiny of VZIG administration records held by …

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  • Contributors JB, JC, PH, JB, RS, and SH contributed on behalf of the Supportive Care Group of the Children's Cancer and Leukaemia Group.

  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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