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The clinical picture of adenovirus infection in children is variable including fever, cough, tonsillitis, keratoconjuctivitis, acute otitis media, febrile convulsions and gastroenteritis. In contrast to other respiratory viruses, half of the children with adenovirus infection have elevated total white blood cell counts (WBC) and serum C reactive protein (CRP) levels making it difficult to differentiate this viral infection from a bacterial one.1 2 Plasma procalcitonin (PCT) increases within 4–6 h after initiation of bacterial infection.3 The normal level of PCT in non-infected persons is under 0.05 ng/ml, and an increase to 0.5 ng/ml …
Funding This work was supported by the Finnish Medical Foundation.
Competing interests None.
Ethics approval Ethics approval by Turku University Hospital Ethics Committee.
Provenance and peer review Not commissioned; externally peer reviewed.