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Plasma procalcitonin levels in children with adenovirus infection
  1. Varpu Elenius1,
  2. Ville Peltola1,
  3. Olli Ruuskanen1,
  4. Minna Ylihärsilä2,
  5. Matti Waris2
  1. 1Department of Paediatrics, Turku University Hospital, Turku, Finland
  2. 2Department of Virology, University of Turku, Turku, Finland
  1. Correspondence to Varpu Elenius, Department of Paediatrics, Turku University Hospital, Box 52, 20521 Turku, Finland; varpu.elenius{at}

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The clinical picture of adenovirus infection in children is variable including fever, cough, tonsillitis, keratoconjuctivitis, acute otitis media, febrile convulsions and gastroenteritis. In contrast to other respiratory viruses, half of the children with adenovirus infection have elevated total white blood cell counts (WBC) and serum C reactive protein (CRP) levels making it difficult to differentiate this viral infection from a bacterial one.1 2 Plasma procalcitonin (PCT) increases within 4–6 h after initiation of bacterial infection.3 The normal level of PCT in non-infected persons is under 0.05 ng/ml, and an increase to 0.5 ng/ml …

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  • Funding This work was supported by the Finnish Medical Foundation.

  • Competing interests None.

  • Ethics approval Ethics approval by Turku University Hospital Ethics Committee.

  • Provenance and peer review Not commissioned; externally peer reviewed.