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Sustained benefits of continuous subcutaneous insulin infusion
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  • Published on: 13 March 2012
    Longitudinal CSII studies warrant a more refined statistical approach than simple t-tests
    • Akash Sinha, Research Fellow, Paediatric Endocrinology Spr
    • Other Contributors:
      • Matt Thomas, Steve Rushton, Tim Cheetham

    Dear Sir,

    We read with interest the observations made by Hughes et al but it is important for readers to be aware of the limitations of their means of data analysis.

    Hughes et al have combined all the pre-CSII HbA1c values and calculated a mean HBA1c (Referred to as Pre-CSII HbA1c) and then compared this with subsequent post CSII HBA1c measurements at different time points. The problem with this method...

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    Conflict of Interest:
    None declared.