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Cost effectiveness of microarray testing for children with global developmental delay

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Microarray testing (array-based comparative genome hybridisation, aCGH) provides whole genome analysis at a much higher resolution than conventional karyotyping. After routine clinical and laboratory testing with negative results aCGH provides a diagnosis in about 6% of children with non-syndromal global developmental delay (GDD). For selected patients this figure could rise to 11% with low resolution …

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  • Competing interests None.

  • Provenance and peer review Commissioned; internally peer reviewed.