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Emotional and behavioural difficulties in chronic granulomatous disease
  1. Theresa S Cole1,
  2. Laura K R Jones2,
  3. Paraic McGrogan3,
  4. Mark S Pearce4,
  5. Terry J Flood5,
  6. Andrew J Cant5,
  7. David Goldblatt6,
  8. Adrian J Thrasher6,
  9. Andrew R Gennery1,
  10. Fiona McKendrick7,
  11. Penny Titman8
  1. 1Institute of Cellular Medicine, Newcastle University, Newcastle, UK
  2. 2Department of Paediatrics, Royal Hospital for Sick Children, Edinburgh, UK
  3. 3Department of Paediatric Gastroenterology, Royal Hospital for Sick Children, Glasgow, UK
  4. 4Institute of Health & Society, Newcastle University, Newcastle, UK
  5. 5Paediatric Immunology & Infectious Diseases Department, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle, UK
  6. 6Institute of Child Health, University College London, London, UK
  7. 7Department of Health Psychology, Newcastle & North Tyneside NHS Trust, Newcastle, UK
  8. 8Department of Psychosocial Services, Great Ormond Street Hospital, London, UK
  1. Correspondence to Dr Theresa S Cole, Paediatric Immunology & Infectious Diseases Department, Old Children's Outpatients, Royal Victoria Infirmary, Queen Victoria Road, Newcastle NE1 4LP, UK; theresa.cole{at}ncl.ac.uk

https://doi.org/10.1136/archdischild-2011-300780

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    Chronic granulomatous disease (CGD) is a rare primary immunodeficiency, characterised by life-threatening bacterial and fungal infections and inflammatory complications.1 Cognitive difficulties are also described.2 Chronic ill health and cognitive difficulties potentially expose patients to psychological difficulties. We analysed data in a national cohort of patients with CGD to understand how these difficulties might manifest.

    Physicians enrolled patients in the national CGD registry between 2000 and 2001.1 …

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    Footnotes

    • Funding The UK and Ireland CGD registry was funded by the CGD Research Trust.

    • Competing interests None.

    • Ethics approval The study was approved by Northern & Yorkshire REC.

    • Provenance and peer review Not commissioned; internally peer reviewed.