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Should we screen children with type 1 diabetes for Addison's disease?
  1. Amir Babiker,
  2. Emily R Leach,
  3. Vipan Datta
  1. Norfolk and Norwich University Hospital, Norwich, UK
  1. Correspondence to Dr Vipan Datta, Norfolk and Norwich University Hospital, Norwich, UK; vipan.datta{at}

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Children with type 1 diabetes mellitus (T1DM) are at a higher risk of developing other autoimmune diseases. The National Institute of Clinical Excellence guidance in 2009 included recommendations about screening for thyroid disease (TD) and coeliac disease (CD) in children with T1DM, but there was no guidance regarding screening for autoimmune Addison's disease (AD).1

Symptoms of AD in children with T1DM include recurrent hypoglycaemia with falling insulin requirements and/or salt craving. Eight per cent of patients with AD require annual hospital treatment for adrenal crisis.2 This …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed