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‘Lest we forget…’
  1. Pramod Mainie1,
  2. Daniel Hawcutt2
  1. 1Whipps Cross Hospital, London, UK
  2. 2Division of Developmental and Reproductive Medicine, University of Liverpool, Liverpool, UK
  1. Correspondence to Pramod Mainie, Whipps Cross Hospital, Whipps Cross Road, Leytonstone, London E11 1NR, UK; pramodmainie{at}

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We read with great interest the leading article ‘Lest we forget…’.1 The authors give a compelling account, against a historical background, of the importance of ethical review of research trials, and the tension between improving the health of the paediatric population versus the rights of the individual child.

Although there is a lot of truth in the ‘therapeutic orphan’ status of paediatric patients (given the historical dearth of pharmacological research in paediatrics), there is an opportunity for any clinician involved …

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  • Competing interests Both authors are members of the MHRA Trainee Doctors Advisory Board.

  • Provenance and peer review Not commissioned; internally peer reviewed.