Article Text

Download PDFPDF
Lactose intolerance in infants: harder to investigate now following discontinuation of Clinitest
  1. Chin Kien Chong,
  2. James Bunn,
  3. Paul Newland
  1. Alder Hey Children's NHS Foundation Trust, Liverpool, UK
  1. Correspondence to Chin Kien Chong, Alder Hey Children's NHS Foundation Trust, Alder Hey Hospital, Eaton Road, West Derby, Liverpool L12 2AP, UK; drckchong{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

In July 2010 Clinitest tablets were withdrawn from the market by Bayer. This commercial quantitative Benedict's reagent test has been used since 1964 for the diagnosis of lactose intolerance in children with diarrhoea.1 It is a non-specific test for the presence of reducing sugars. Clinically significant lactose intolerance has conventionally been determined when stool-reducing sugars are ≥0.5%.2 In recent years Clinitest has been complemented by chromatography to identify the reducing sugar present as lactose. Clinitest can be done rapidly and as a near patient test, allowing therapeutic decisions regarding withdrawal of lactose from the diet.

Following the discontinuation of Clinitest we were …

View Full Text


  • Competing interests None.

  • Ethics approval This study was conducted with the approval of the Alder Hey Children's NHS Foundation Trust Audit Committee.

  • Provenance and peer review Not commissioned; internally peer reviewed.