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Cerebral palsy rates by birth weight, gestation and severity in North of England, 1991–2000 singleton births
  1. Svetlana V Glinianaia,
  2. Judith Rankin,
  3. Allan Colver,
  4. for the North of England Collaborative Cerebral Palsy Survey
  1. Institute of Health and Society, Newcastle University, Newcastle upon Tyne, England, UK
  1. Correspondence to Dr Svetlana Glinianaia, Institute of Health and Society, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK; svetlana.glinianaia{at}


Objective To investigate changes in rates of cerebral palsy (CP) by birth weight, gestational age, severity of disability, clinical subtype and maternal age in the North of England, 1991–2000.

Methods Data on 908 cases of CP (816 singletons, 92 multiples) were analysed from the prospective population-based North of England Collaborative Cerebral Palsy Survey. Severity of disability, measured as a Lifestyle Assessment Score (LAS), was derived from the lifestyle assessment questionnaire. CP rates by birth weight, gestational age, birth weight standardised for gestational age and sex, severity of disability and maternal age were compared between 1991–1995 and 1996–2000 using rate ratios (RR).

Results The prevalence of CP in singletons was 2.46 (95% CI 2.29 to 2.63) per 1000 neonatal survivors compared to 11.06 per 1000 (95% CI 8.81 to 13.3) in multiples (RR 4.49, 95% CI 3.62 to 5.57), with no significant change between quinquennia. The singleton CP rates were higher for lower birth weight groups than birth weight ≥2500 g; and there were no significant changes for any birth weight group between quinquennia. There were also no changes in rates of more severe disability (LAS≥30%) by birth weight, gestation or clinical subtype. For preterm and term births the patterns of Z-score of birth weight-for-gestation are similar, with CP rates increasing as Z-score deviates from the optimal weight-for-gestation, which is about 1 SD above the mean.

Conclusions In contrast to increasing rates in previous years, rates of CP and more severe CP were stable by birth weight, gestational age and clinical subtype for 1991–2000.

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  • The collaborators during the period of data collection were: R Carpenter and R Willoughby, Darlington; S Pandy and N Cookey, Durham; A Paynter and P Whitehead, East Cumbria; R Menzies, Gateshead; K Agrawal, Hartlepool; M Gibson and S Wariyar, Newcastle; C Jessen, Northumberland; B Kurup, North Tees; E Lee, South Tees; H Palmer and N Brewster, South Tyneside; A Johnson, South West Durham; K Horridge, Sunderland; S Precious, S Bilsberry and V Wood, West Cumbria

  • Funding JR is funded by a Personal Award Scheme Career Scientist Award from the National Institute of Health Research (UK Department of Health). Administrative support for the NECCPS, as part of the Northern Regional Maternity Survey Office, is funded by the Regional Health Authority, District Health Authorities and Primary Care Trusts.

  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.