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Question 1 Is there an increased risk of necrotising enterocolitis in preterm infants whose mothers' expressed breast milk is fortified with multicomponent fortifier?
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  • Published on:
    Reply to "This question deserves a more indepth review"
    • Iain Martin
    • Other Contributors:
      • David Quine, Lesley Jackson

    Dear Archimedes,

    We thank Dr Gallagher for his interesting contribution, and welcome further debate on this topic.

    While we agree that in the study from Schanler et al. fortifier is used in all infants when on >100ml/kg/day of milk, one can draw the conclusion that early fortification does not change the risk of NEC. The use of fortifier above 100 ml/kg/day, however, may attenuate the overall effe...

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    Conflict of Interest:
    None declared.
  • Published on:
    This question deserves a more indepth review

    Dear Archimedes, This is a very important question and one that deserves more consideration. Many health care staff looking after these vulnerable infants do recognise that some of them seem to develop poor feed tolerance after addition of fortifier. The papers used to support the conclusion that fortification does not appear to increase the risk of NEC deserve a rereading by the authors. The paper by Schanler et al is p...

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    Conflict of Interest:
    None declared.