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Anxiety is more common in children with asthma
  1. P J Vuillermin1,2,3,
  2. S L Brennan1,
  3. C F Robertson2,3,
  4. J B Carlin2,3,
  5. M Prior2,3,
  6. B M Jenner1,
  7. M South2,3
  1. 1Child Health Research Unit, Barwon Health, Geelong, Australia
  2. 2Murdoch Childrens Research Institute, Parkville, Australia
  3. 3Department of Paediatrics, University of Melbourne, Parkville, Australia
  1. Correspondence to Dr Peter Vuillermin, Child Health Research Unit, Barwon Health, PO Box 281, Ryrie Street, Geelong 3220, Australia; peterv{at}


Objective There are a variety of reasons why there may be an association between asthma and anxiety in children. Research into the relation between asthma and anxiety has been limited by the sole use of parent-reported or self-reported asthma symptoms to define asthma status. The objective of this study was to determine if children with physician-defined asthma are more likely to suffer anxiety than children without asthma.

Design A population-based, cross-sectional assessment, of self-reported anxiety symptoms.

Setting and participants Children aged 5–13 years from Barwon region of Victoria, Australia. Asthma status was determined by review with a paediatrician. Controls were a sample of children without asthma symptoms (matched for age, gender and school).

Outcome measure The Spence Children's Anxiety Scale (SCAS) written questionnaire. The authors compared the mean SCAS score, and the proportion of children with an SCAS score in the clinical range, between the groups.

Results Questionnaires were issued to 205 children with asthma (158 returned, response rate 77%), and 410 controls (319 returned, response rate 78%). The SCAS scores were higher in asthmatics than controls (p<0.001); and were more likely to be in the clinical range (OR=2.5, 95% CI 1.1 to 5.8, p=0.036). There was no evidence that these associations could be explained by known confounding factors.

Conclusions Children with asthma are substantially more likely to suffer anxiety than children without asthma. Future studies are required to determine the sequence of events that leads to this comorbidity, and to test strategies to prevent and treat anxiety among children with asthma.

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  • Competing interests This project was funded by the Jack Brockhoff Foundation, the Murdoch Childrens Research Institute and the National Health and Medical Research Council of Australia.

  • Ethics approval This study was conducted with the approval of the Barwon Health, Geelong,Victoria, Australia.

  • Provenance and peer review Not commissioned; externally peer reviewed.