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Chlamydia trachomatis respiratory infection in Dutch infants
  1. G I J G Rours1,5,
  2. M R Hammerschlag2,
  3. G J J Van Doornum3,
  4. W C J Hop4,
  5. R de Groot1,
  6. H F M Willemse5,
  7. H A Verbrugh5,
  8. R P Verkooyen5
  1. 1
    Division of Paediatric Infectious Diseases & Immunology, Department of Paediatrics, Erasmus MC, Rotterdam, The Netherlands
  2. 2
    Division of Pediatric Infectious Diseases, Department of Pediatrics, State University of New York Downstate Medical Center, Brooklyn, New York, USA
  3. 3
    Department of Virology, Erasmus MC, Rotterdam, The Netherlands
  4. 4
    Department of Epidemiology & Biostatistics, Erasmus MC, Rotterdam, The Netherlands
  5. 5
    Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands
  1. Correspondence to Dr G I J G Rours, Department of Paediatrics, Erasmus MC, Dr Molewaterplein 60, 3015 GJ Rotterdam, The Netherlands; g.rours{at}


Chlamydia trachomatis is the most common bacterial pathogen causing sexually transmitted infections in Dutch adults. As prenatal screening for C trachomatis and treatment of pregnant women is not routine practice in The Netherlands, perinatal transmission of C trachomatis may therefore occur. The presence of C trachomatis in infants less than 6 months of age who presented with respiratory complaints to the Erasmus MC-Sophia hospital was evaluated. Respiratory specimens, primarily nasopharyngeal swabs, were tested for C trachomatis, respiratory viruses and Mycoplasma pneumoniae using PCR, viral isolation in cell cultures and direct immunofluorescence. C trachomatis respiratory tract infection was confirmed to be relatively common with detection in 10 of 148 (7%) infants tested. C trachomatis had not been tested for by the attending physicians, but was the second most frequently detected respiratory pathogen after human Respiratory Syncitial Virus, which was found in 41 (28%) infants.

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  • Competing interests None.

  • Ethics approval Ethics approval was provided by Erasmus MC.