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Here’s an unusual source of vitamin D (British Journal of General Practice 2008;58:644–5). A 30-year-old vegetarian Indian man living in southeast England was found to be vitamin D deficient. He was provided with vitamin D tablets but decided to treat himself after doing his own research. He bought an ultraviolet B (UVB) bulb from a hardware shop and shone the light onto about 200g of button mushrooms from a distance of about 15 cm before stir-frying and eating the mushrooms. After doing this daily for 3 months in winter his serum concentration of 25-hydroxyvitamin D had increased from 17 to 39 nmol/l (normal range 25-120 nmol/l) and his serum parathyroid hormone concentration fell from 9.3 to 5.6 pmol/l (normal range 1.6 – 6.9 pmol/l). Edible mushrooms contain ergocalciferol and irradiating them with UVB increases the vitamin D content.
The inherited forms of epidermolysis bullosa are complex, with approximately 25 distinct phenotypes and hundred of genotypes involving at least 10 genes. The four major types are epidermolysis bullosa simplex, junctional epidermolysis bullosa, dominant dystrophic epidermolysis bullosa, and recessive dystrophic epidermolysis bullosa. There have been case reports of cardiomyopathy in patients with recessive dystrophic epidermolysis bullosa (RDEB) and now a study using data from the US National Epidermolysis Bullosa Registry and including 3280 …