We prospectively studied 124 consecutive hypoglycaemia screens performed on children attending our emergency department over a 27-month period (March 2006 to May 2008). In keeping with most other paediatric services in the UK, we routinely collect a number of samples to permit investigation of low blood sugar, including metabolic investigations, and a random cortisol and growth hormone. Most of these patients have an intercurrent illness and are subsequently thought to have had an episode of “physiological hypoglycaemia”. There is a paucity of published data examining how cortisol and growth hormone respond to hypoglycaemia and no previous work looking at …