When should oxygen be given to children at high altitude? A systematic review to define altitude-specific hypoxaemia
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  • Richard G Fiddian-Green
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    Subhi et al have asked when oxygen should be given to children at high altitude observing that hypoxaemia is the most common fatal complication in deaths occurring from pneumonia in children in developing countries (1). Might the answer be never?

    Supplementary oxygen appears to be harmful in climbers on Everest possibly because it eliminates the up-regulation of oxidative phosphorylation by mass action by hypoc...

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