Article Text

  1. S Wikström1,
  2. I Hansen-Pupp2,
  3. D Ley2,
  4. V Fellman2,
  5. I Rosén3,
  6. L Hellström-Westas2,4
  1. 1Department of Paediatrics, Karlstad Central Hospital, Karlstad, Sweden
  2. 2Department of Paediatrics, Lund University Hospital, Lund, Sweden
  3. 3Department of Clinical Neurophysiology, Lund University Hospital, Lund, Sweden
  4. 4Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden


Objective To investigate if early amplitude integrated EEG (aEEG) correlates with short-term outcome in extremely preterm infants.

Methods aEEG was recorded the first 72 h of life (mean duration 52.8 h) in 45 infants, 22–27 gestational weeks. The recordings were analysed in 4-h époques and scored for continuity, cyclicity, lower border amplitude and bandwidth (Burdjalov et al, Pediatrics 2003;112:855–61). Evaluation of the “real” EEG was included in a second scoring.

Results Infants with good outcome had higher aEEG maximum scores during the first 48 and 72 h, respectively. aEEG maximum scores during the first 24 h correlated with gestational age (rs  =  0.399, p = 0.043) and 5-minute Apgar score (rs  =  0.460 p = 0.018) in infants with good outcome. Maximum aEEG scores increased from 0–24 h to 24–48 h in infants with good outcome (paired tests, p = 0.026). The associations were stronger when the evaluation of the “real” EEG was included.

Conclusion Overall aEEG background activity correlates with outcome already during the first days of life in extremely preterm infants.

Wikström et al

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