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THE STATISTICAL EVALUATION OF ANAEMIA FOR CHILDREN EXPOSED TO HEAVY METALS IN THE COPSA MICA AREA
  1. S I Iurian1,
  2. M L Neamtu1,
  3. B Neamtu1
  1. 1Pediatric Clinic, Pediatric Hospital, Sibiu, Romania

Abstract

Objectives To evaluate the risk of anaemia for exposed children to lead and cadmium in the Copsa Mica area. To confirm that anaemia for exposed populations represents a risk factor for lead intoxication (Copsa Mica was one of the most polluted town in Europe).

Methods Two groups were studied: the 1st group consists of 90 children exposed to heavy metals (statistically significant group) and the 2nd group was represented by 88 children from non-exposed locations. Both groups are homogenous (no statistical differences regarding the age and sex ratio). Inclusion criteria: children between 2 and 16 years of age and no haematopoiesis anomalies. Tests performed: blood lead level (BLL μg%), cadmium blood level and haematological evaluation (haemoglobin value and erythrocyte parameters). For statistical evaluation of the results, the authors have used “independent-sample t test” and Taro–Yamman formula.

Results The mean value for BLL in the exposed group was 11.15 μg% compared with 1.95 μg% for the 2nd group (p = 0.000). The cadmium blood levels were normal for the two groups. The mean value of haemoglobin for the 1st group was 12.850 g% compared with the second group (12.943 g%). In addition, there was a significant difference regarding the mean cell haemoglobin concentration (MCHC; p = 0.000).

Conclusions Although the children from the Copsa Mica area are still exposed to lead, there is no risk of anaemia in exposed children; there is a significant statistical difference for MCHC in both groups.

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