Article Text

  1. S Fouzas1,
  2. D Bougioukou1,
  3. A Varvarigou1,
  4. S Mantagos1
  1. 1Department of Pediatrics, School of Medicine, University of Patras, Patras, Greece


Background and Aims Determination of transcutaneous bilirubin (TcB) represents a reliable non-invasive method for assessing neonatal bilirubinaemia. The aim of our study was to develop an hour-specific TcB nomogram for term and near-term neonates.

Methods Serial TcB measurements (Bilicheck bilirubinometer) were performed at designated times during the first 96 h of life, in healthy neonates (gestational age >35 weeks and birth weight >2000 g), from September 2005 to August 2007. The 5th, 25th, 50th, 75th and 95th percentiles of TcB measurements were calculated and plotted on an hour-specific nomogram.

Results In total, 8195 TcB measurements were performed in 1685 newborn infants. Ninety (5.4%) neonates developed serious hyperbilirubinaemia and underwent phototherapy. The hour-specific TcB nomogram is presented in the fig.

Conclusions TcB levels in healthy newborn infants increased according to a particular pattern during the first 96 h of life. We present an hour-specific TcB nomogram for healthy term and near-term neonates.

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