Article Text
Abstract
Background and Aims Determination of transcutaneous bilirubin (TcB) represents a reliable non-invasive method for assessing neonatal bilirubinaemia. The aim of our study was to develop an hour-specific TcB nomogram for term and near-term neonates.
Methods Serial TcB measurements (Bilicheck bilirubinometer) were performed at designated times during the first 96 h of life, in healthy neonates (gestational age >35 weeks and birth weight >2000 g), from September 2005 to August 2007. The 5th, 25th, 50th, 75th and 95th percentiles of TcB measurements were calculated and plotted on an hour-specific nomogram.
Results In total, 8195 TcB measurements were performed in 1685 newborn infants. Ninety (5.4%) neonates developed serious hyperbilirubinaemia and underwent phototherapy. The hour-specific TcB nomogram is presented in the fig.
Conclusions TcB levels in healthy newborn infants increased according to a particular pattern during the first 96 h of life. We present an hour-specific TcB nomogram for healthy term and near-term neonates.