Abstract

Chamomile has a healing property with anti-inflammatory, antibacterial and antifungal activity and is applied topically to relieve pain.

We selected this plant for a preliminary clinical trial study on decreasing teething symptoms such as irritability, mouthing and drooling in 6–12-month-old infants in comparison with placebo.

We evaluated 62 infants with teething symptoms in a double-blind prospective placebo-controlled clinical trial for 4 days topical use of drug; questionnaires about infant signs and symptoms before and after treatment were filled in. Infants with any systemic illness were excluded.

The results indicated a significant effect of chamomile water extract on relieving teething symptoms, especially pain, which caused irritability, compared with placebo (p<0.0001).