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Management of infantile spasms in a regional centre before and after the United Kingdom infantile spasms study (UKISS)
  1. N Maheshwari1,
  2. Z Zaiwalla2,
  3. M A McShane3
  1. 1
    Paediatric Neurology, John Radcliffe Hospital, Oxford, UK
  2. 2
    Park Hospital, Oxford, UK
  3. 3
    John Radcliffe Hospital, Oxford, UK
  1. Nitin Maheshwari, Specialist registrar, Paediatric Neurology, John Radcliffe Hospital, Oxford, UK; nitin023{at}

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The United Kingdom Infantile Spasms Study (UKISS)1 compared hormonal treatment for the management of infantile spasms with treatment with vigabatrin. This study showed that cessation of spasms was more likely in infants given hormonal treatment. We believe that this study has changed our practice and the advice we give colleagues across our region regarding the management of infantile spasms. We undertook this audit to see if this could be confirmed.

All infants with EEGs within the …

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  • Funding: None.

  • Competing interests: None.