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Letter
Long-term health outcomes of neonatal screening for cystic fibrosis
  1. F Festini1,
  2. G Taccetti2,
  3. V Galici1,
  4. S Campana3,
  5. G Mergni3,
  6. T Repetto3
  1. 1
    University of Florence, Department of Paediatrics, Florence, Italy
  2. 2
    Cystic Fibrosis Centre of Tuscany, Meyer Children Hospital, Florence, Italy
  3. 3
    Cystic Fibrosis Centre of Tuscany, Meyer Children Hospital, Florence, Italy
  1. Professor Filippo Festini, University of Florence, Department of Paediatrics, Florence, Italy, Via L.Giordano 13, 50132 Florence, Italy; filippo.festini{at}unifi.it

https://doi.org/10.1136/adc.2008.137067

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    Balfour-Lynn’s review1 underlines the benefits of neonatal screening programmes for cystic fibrosis (CFNSP). However, long-term clinical outcomes still need to be clarified. In particular, only a few published studies have compared the clinical outcomes at age 15 years of screened and non-screened cystic fibrosis (CF) patients.2–4 In Tuscany, Italy (3.5 million inhabitants, CF incidence 1 in 4144)5 a CFNSP has been carried out since 1984 together with a centralised follow-up programme. We wanted to evaluate the clinical benefits of CFNSP in an entire population of CF patients 15 years after diagnosis. To this purpose, we compared the clinical conditions of CF patients born in Tuscany since the introduction of the CFNSP and diagnosed by screening with those of patients followed since diagnosis by our centre and born in the same period but diagnosed …

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    Footnotes

    • Funding: Some of the data from this study were presented in oral form at the 27th European Cystic fibrosis Conference, European Cystic Fibrosis Society, Birmingham, UK, 13-17 June, 2004 and published in the Conference proceedings.

    • Competing interests: The Authors declare that they don’t have any competing interest that may affect the results of this study.