Article Text

Download PDFPDF
Severe iron intoxication treated with exchange transfusion
  1. M Carlsson1,
  2. D Cortes2,
  3. S Jepsen1,
  4. T Kanstrup3
  1. 1
    Pediatric Intensive Care Unit, Odense University Hospital, Odense, Denmark
  2. 2
    Department of Pediatrics, Odense University Hospital, Odense, Denmark
  3. 3
    Department of Clinical Immunology, Odense University Hospital, Odense, Denmark
  1. Dr Marcela Carlsson, Pediatric Intensive Care Unit, Afdeling V, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C., Denmark; marcelacarlsson{at}


An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 μg/dl (244 μmol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 μg/dl (24 μmol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Competing interests: None.

  • Ethics approval: Parental/guardian informed consent was obtained for publication of the person’s details in this report.