Article Text

Download PDFPDF
Angiotensin II receptor blockers to slow aortic root dilation in Marfan’s syndrome

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Marfan’s syndrome is an autosomal dominant condition affecting about 1 in 5000 people and is caused by mutations in the gene (FBN1) that encodes fibrillin-1. The main cause of premature death in people with Marfan’s syndrome is progressive dilation of the aortic root leading to dissection. Current medical treatment is mainly with β blockers. Experiments …

View Full Text