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Competing interests: PC received a travel bursary from Roche (UK) Ltd in 2004 to present a research study of Konakion Neonatal in preterm infants at an international meeting. MJS received laboratory funding from F. Hoffmann-La Roche Ltd, Basel, Switzerland for performing analytical assays (vitamin K1 and PIVKA-II) for pre- and post-licensing studies of Konakion MM Paediatric.