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Live viral vaccines in a DiGeorge syndrome patient
  1. V Waters1,
  2. K S Peterson2,
  3. P LaRussa3
  1. 1Department of Pediatrics, Division of Infectious Diseases, Hospital for Sick Children, University of Toronto, Toronto, Canada
  2. 2Department of Pediatrics, Division of Allergy and Immunology and Division of Autoimmune and Molecular Diseases, Columbia University, New York, NY 10032, USA
  3. 3Department of Pediatrics, Division of Infectious Diseases, Columbia University, New York, NY 10032, USA
  1. Correspondence to:
    Dr Valerie Waters
    Division of Infectious Diseases, The Hospital for Sick Children, 555 University Avenue, Rm 7289, Toronto, Ontario, Canada M5G 1X8; Valerie.waters{at}


We report a case of pneumonia in a 13 month old male child with partial DiGeorge syndrome who died after inadvertently receiving live viral vaccines. Although live viral vaccines have been used safely in some children with DiGeorge syndrome, there are insufficient data to recommend their routine use in those with severe immunodeficiency.

  • DiGeorge syndrome
  • vaccine
  • viral

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  • Published Online First 23 June 2006

  • The corresponding author and co-authors declare that there are no competing interests

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