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The UK Newborn Screening Programme has set standards for the identification, investigation and early management of children with congenital hypothyroidism.1 The standards state that infants with a blood spot thyroid-stimulating hormone (TSH) concentration greater than 20 mU/l are considered to have a positive screening result and referred for investigation by a designated clinician as defined by the British Society for Paediatric Endocrinology and Diabetes. Infants with an initial blood spot TSH concentration between 10 mU/l and 20 mU/l are considered to have a “borderline” result, and the assay is repeated. If the concentration remains greater than 10 mU/l on reassay, a repeat blood sample is collected. If the repeat blood spot result is greater than or equal to 10 mU/l this is …
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