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Endocrinology and diabetes

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L. Haines1, K. Wan1, T. Barrett2, J. Shield3.1Royal College of Paediatrics and Child Health, London, UK; 2Birmingham Children’s Hospital, Birmingham, UK; 3Bristol Royal Hospital for Sick Children, Bristol, UK

Aims: To establish the incidence of non-type 1 diabetes and the incidence of obesity related type 2 diabetes in children 0–16 years in the British Isles during the period from October 2004 to October 2005.

Methods: Monthly surveillance of new cases (suspected or confirmed) of non-type 1 diabetes in children under 17 years in the UK and Ireland through the British Paediatric Surveillance Unit. A parallel two-monthly reporting scheme was set up using diabetes nurse specialists to identify any cases not seen by paediatricians.

Results: 145 cases (81 girls, 64 boys) of physician-diagnosed non-type 1 diabetes have been notified to date; these included 57% (83) cases of type 2 diabetes, 28 (19%) cases of diabetes secondary to another condition, 12% (17) cases of maturity onset diabetes of the young (MODY), and 12% (17) cases of syndromic diabetes. Confirmation of the diagnosis will be obtained by follow up one year after diagnosis. Of the 83 physician-diagnosed type 2 cases, 37 were boys and 46 girls; overall 96% were overweight and 83% obese according to International Obesity Task Force cut offs. The ages ranged from 9.9 to 16.8 years and the mean age was 13.4 (SD 1.7) for girls and 14.1 (SD 1.8) for boys. In 89% of cases there was a family history of type 2 diabetes, 65% of which were in first-degree relatives. 60% of cases were in white children compared to 40% from an ethnic minority origin, of which South Asian and Black children made up 42% and 36%, respectively.

Conclusion: Preliminary results suggest an incidence in under …

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